Artemis One Health

TBEV-COMEIN – Tick-borne encephalitis (TBEV)

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TBEV-COMEIN – Tick-borne encephalitis Research

Ticks are able to transmit a wide range of diseases to both humans and animals, including Lyme’s disease and tick-borne encephalitis (TBE). TBE, a disease caused by the tick-borne encephalitis virus (TBEV), is often associated with neurological symptoms in humans.

It can be found across Eurasia and spans from Japan throughout Asia into Europe. Despite the presence of TBEV in many parts of Germany, the virus was never detected in the Netherlands. Recently, however, TBEV-positive antibodies were found in roe deer and the virus was also isolated from ticks, confirming the presence of the virus in The Netherlands. Soon after, the first cases of TBE in humans presented themselves. As a virus can often spread rapidly after its initial introduction, it is important to study the risk of further TBEV transmission within the Netherlands. As a result, a collaborative project between Artemis One Health, Wageningen and RIVM, titled TBEV-COMEIN and funded by ZonMW.

The aim of this project is:

  • Identifying high-risk areas for ticks based on ecological conditions and biodiversity of reservoir hosts, such as rodents and deer
  • Studying the occurrence and role of ‘co-feeding’ transmission of TBEV in relation to climate
  • Mapping the presence of the virus in ticks and antibodies in reservoir hosts
  • Genetic analyses of isolated virus to determine the origin of the virus

The ultimate goal of the project is to contribute to an “early warning” system in the Netherlands and provide a stepping stone to combat this viral disease.

Status: Ongoing…


TBEV-COMEIN project is funded by ZonMW, Non-alimentaire zoonosen, Project number 58466-2.



Artemis One Health Research Foundation (NL)

Wageningen University (WUR) (NL)

National Institute for Public Health (RIVM) (NL)

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