Artemis One Health
GRANT-DRIVEN Projects, ZAPI
ZAPI aims to shorten the time to adequately respond to emerging infectious diseases using a One Health approach (http://zapi-imi.eu). The project will yield platforms for the rapid identification and production of viral domains that can be used as veterinary vaccines and will yield platforms for the rapid development, selection and production of protective antibodies to protect the human population. The project will not only aim at rapid development of these products, but also ensure fast track registration and implementation of the control tools as soon as possible after pathogen emergence. To develop these pipelines, the project will focus on three priority pathogens (Rift Valley fever virus, Schmallenberg virus and Middle East Respiratory Syndrome Coronavirus).
The main goals of ZAPI are:
- Platforms that are suitable for rapid surge production of vaccines.
- Platforms that allow the rapid identification and production of antibodies capable of neutralizing emerging viruses.
- Development of release assays that do not make use of animals.
- Development of protocols for fast-track registration of developed products.
Artemis One Health is involved in evaluation of the immunogenicity and protective efficacy of the developed candidate vaccines and neutralizing reagents.
The ZAPI project is supported by the Innovative Medicines Initiative Joint Undertaking (IMI JU), with funding from the EU FP7 Programme.
The project brings together 20 European partners from academia, industry and regulatory specialists with a budget of over 20 m€ and will have a duration of 5 years. This platform will build on close collaborative partnerships between human and veterinary medical institutions, governmental regulatory agencies, expert academic groups and industrial partners, within the scope of a broad spectrum of existing EU-funded consortia and initiatives.
Harbour Antibodies Rotterdam
Artemis One Health Research
Dyadic NDL Wageningen
PUBLIC CONSORTIUM PARTNERS
Stiftung Tierärztliche Hochschule Hannover (TiHo)
Institut de Recerca i Tecnologia Agroalimentries (IRTA/ex-CReSA)
Agencia Estatal Consejo Superior de Investigaciones Cientificas (CSIC)
Universitätsklinikum Bonn (UKB)
International Alliance for Biological Standardization Institut Pasteur Friedric-Loeffler-Institut (FLI)
Leiden University Medical Center (LUMC)
Faculty of veterinary Medicine Central Veterinary Institute
Erasmus Medical Center
AstraZeneca / Medimmune
Boehringer Ingelheim Animal Health